AG 490
AG 490
- CAS:
- 134036-52-5
- MF:
- C17H14N2O3
- MW:
- 294.3
Suppliers by country/region
Company Type
Properties
- Melting point:
- 215
- Boiling point:
- 615.2±55.0 °C(Predicted)
- Density
- 1.337±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- ethanol: 5 mg/mL
- pka
- 8.82±0.35(Predicted)
- form
- solid
- color
- yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-50-25
- Safety Statements
- 26-36-61-45
- WGK Germany
- 1
- Hazard Note
- Irritant/Keep Cold under -20C
- HS Code
- 2926907090
Use
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
0 India supplier list of "AG 490"
- Product Name:AG-490
- Products Intro:Brand:clearsynth | Product Number:CS-T-01450
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:AG 490
- Products Intro:Purity: 95%-99% 604crystal | Package: 1KG;0.01USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:AG 490
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AG-490
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: AG-490
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:AG 490
- Company Type: Manufacturer
- Country/Region: CHINA
- Product Name:2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A806722
- Company Type: Reagent
- Country/Region: CHINA
-
25mg$178.00
- Product Name:TyrphostinB42
- Products Intro:Brand：Alfa Aesar | Product Number：J61715 | Purity：99+%
- Company Type: Trader
- Country/Region: UNITED STATES
-
25mg$124.00100mg$327.00
- Product Name:Tyrphostin AG 490 >99%
- Products Intro:Brand: Apollo Scientific | Product Number: BIT1100
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Main Products: cof,mof
-
10$124.00
- Product Name:AG490
- Products Intro:Brand：Tocris Bioscience | Product Number：0414 | Purity：≥99%(HPLC)
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Product Name:(E/Z)-AG490
- Products Intro:Brand：dcchemicals | Product Number：DC44560 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES