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Apoptolidin

Apoptolidin

CAS:
194874-06-1
MF:
C58H96O21
MW:
1129.38

Suppliers by country/region

Company Type

Properties

Melting point:
128-130°
alpha 
21D -5.2° (c = 1.0 in methanol)
Boiling point:
1108.9±65.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
Flash point:
87℃
storage temp. 
-20°C
solubility 
Soluble in DMSO, DMF, ethanol, or methanol.
pka
11.71±0.70(Predicted)
form 
DMSO solution
color 
White
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, ethanol or methanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302-H315-H319
Precautionary statements 
P264-P270-P280-P301+P312-P330-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313-P501
RIDADR 
NA 1993 / PGIII
WGK Germany 
2

Use

Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene (IC50 = 11 ng/ml). Apoptolidin is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action.

0 India supplier list of "Apoptolidin"

Sigma-Aldrich Chemicals Private Limited
  • Product Name:ApoptolidinAReadyMadeSolution
  • Products Intro:Brand:sigma aldrich | Product Number:SML0907 | Purity:1?mg/mLinDMSO
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Apoptolidin
  • Products Intro:Brand:clearsynth | Product Number:CS-CM-00016
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Apoptolidin
  • Products Intro:Purity: >=95% | CustNote: BOC Sciences also provides custom synthesis services for Apoptolidin.
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Product Name:Apoptolidin
  • Products Intro:Purity: >95% | Package: $800.9/100μg;Bulk package | CustNote: >95%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • 500ul$756.00
  • Product Name:Apoptolidin A Ready Made Solution
  • Products Intro:Brand: Sigma-Aldrich | Product Number: SML0907 | Purity: 1 mg/mL in DMSO
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • 100 μg$215.00
    500 μg$860.00
  • Product Name:Apoptolidin
  • Products Intro:Brand: Caymanchem | Product Number: 19435 | Purity: ≥95%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Apoptolidin
  • Products Intro:Brand:a2bchem | Product Number:AD61932
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Apoptolidin
  • Products Intro:Brand:aksci | Product Number:6616CS
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • 100µg$240.00
    250µg$470.00
  • Product Name:Apoptolidin
  • Products Intro:Brand:trc-canada | Product Number:A729048
  • Company Type: Trader
  • Country/Region: CANADA
American Custom Chemicals Corporation
  • 0.1MG$436.00
  • Product Name:APOPTOLIDIN
  • Products Intro:Brand:Acccorporation | OriginalID:API0019258 | Purity:95.00%
  • Company Type: Trader
  • Country/Region: UNITED STATES
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