Apremilast
ApreMilast
- CAS:
- 608141-41-9
- MF:
- C22H24N2O7S
- MW:
- 460.5
Suppliers by country/region
Company Type
Properties
- Melting point:
- 152-156°C
- Boiling point:
- 741.3±60.0 °C(Predicted)
- Density
- 1.381
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 14.01±0.20(Predicted)
- form
- Solid
- color
- White to Pale Yellow
- InChIKey
- IMOZEMNVLZVGJZ-QGZVFWFLSA-N
- SMILES
- C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C
Safety Information
- Symbol(GHS)
GHS08,GHS07
- Signal word
- Warning
- Hazard statements
- H302-H361
- Precautionary statements
- P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501
Use
Apremilast (Otezla) was approved by the FDA on March 21, 2014 for the treatment of adult patients with active psoriatic arthritis. Apremilast is a member of a new class of oral small molecule inhibitors of the phosphosphodiesterase 4 (PDE4) enzyme. When PDE4 is inhibited in immune cells, it results in elevation of intracellular cyclic adenosine monophosphate (cAMP) levels, which can regulate inflammatory mediators. The current clinical data indicate that apremilast is an effective and well tolerated option for the management of psoriasis and PsA in adults.
47 India supplier list of "ApreMilast"
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 125 MG
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast API
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Apremilast
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Telangana,INDIA