Aprepitant
Aprepitant
- CAS:
- 170729-80-3
- MF:
- C23H21F7N4O3
- MW:
- 534.43
Suppliers by country/region
Company Type
Properties
- Melting point:
- 244-246°C
- alpha
- D25 +69° (c = 1.00 in methanol)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in DMSO (>25 mg/ml)
- pka
- 8.06±0.20(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +61 to +71°, c = 1.0 in methanol
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H319-H351
- Precautionary statements
- P501-P202-P201-P264-P280-P308+P313-P337+P313-P305+P351+P338-P405
- HS Code
- 2934990002
Use
Aprepitant is a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
72 India supplier list of "Aprepitant"
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Aprepitant
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:APREPITANT 43% PELLETS
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA