Arecoline hydrobromide manufacturers and suppliers in india

Arecoline hydrobromide

Properties

Melting point:: 171-175 °C

storage temp.: Inert atmosphere,Room Temperature

solubility: H₂O: 0.1 g/mL, clear, colorless

form: Powder

pka: 6.84(at 25℃)

color: White to light yellow

Merck: 14,778

BRN: 3914826

Stability:: Stable for 2 years from date of purchase as supplied. Solutions are not stable – make fresh daily.

InChI: InChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H

InChIKey: AXOJRQLKMVSHHZ-UHFFFAOYSA-N

SMILES: C1(C(=O)OC)=CCCN(C)C1.Br

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P501

Hazard Codes: Xn,T

Risk Statements: 22-23/24/25

Safety Statements: 45-38-36/37/39-28A

RIDADR: 1544

WGK Germany: 3

RTECS: QT2275000

F: 8

HazardClass: 6.1

PackingGroup: III

HS Code: 29399990

Toxicity: LD50 par-rat: 270 mg/kg ABMGAJ 28,681,72

Use

Arecoline hydrobromide is an arecoline salt of hydrobromic acid generally used in removing parasites from dogs intestine1-2. It has been used for almost half a century for the treatment of Echinococcus granulosus in dogs, as an anthelminthic2-4. The vermifuge action of arecoline is due to a combination of factors, including (a) the increased activity of the intestinal glands, resulting in a copious secretion which may tend to loosen the hold of the worms on the mucous membrane, when (b) the increased peristalsis sweeps them onward to be voided with the faeces. It has a strong parasympathomimetic action4. It may have been used as working standard in the determination of arecoline concentration from dog plasma using LCMS/MS1.