Ataluren (PTC124)
Ataluren (PTC124)
- CAS:
- 775304-57-9
- MF:
- C15H9FN2O3
- MW:
- 284.24
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Company Type
Properties
- Melting point:
- 241 - 242°C
- Boiling point:
- 503.7±60.0 °C(Predicted)
- Density
- 1.379
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly)
- form
- White to off-white solid.
- pka
- 3.58±0.10(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20)
- InChIKey
- OOUGLTULBSNHNF-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=CC(C2N=C(C3=CC=CC=C3F)ON=2)=C1
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H336-H373
- Precautionary statements
- P260-P271-P304+P340+P312-P314-P403+P233-P405
- HS Code
- 2933998090
Use
Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 M in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.
1 India supplier list of "Ataluren (PTC124)"
- Product Name:PTC-124-CAS775304-57-9-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:5.30918
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Ataluren 98%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.130436
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Ataluren
- Products Intro:Brand:clearsynth | Product Number:CS-O-10478
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:PTC-124
- Products Intro:Brand:ajchemicals | Product Number:JDH-35843 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Ataluren
- Products Intro:Purity: 0.99 | Package: 1KG;10KG | CustNote: Gold product
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API,Phamaceutical intermediate,fine chemicals,API,Phamaceutical intermediate
- Product Name:Ataluren
- Products Intro:Purity: 98% HPLC | Package: 25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$0.00/ 25KG
- Product Name:Ataluren
- Products Intro:Purity: 99% | Package: 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide
$0.00/ 25kg
- Product Name:Ataluren (PTC124)
- Products Intro:Purity: 99% | Package: 1kg;50USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediates,Peptides,Organic Chemical,Sarm Product,Pharmaceutical Chemical
$50.00/ 1kg
- Product Name:Ataluren
- Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:PTC124
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA