Baclofen
Baclofen
- CAS:
- 1134-47-0
- MF:
- C10H12ClNO2
- MW:
- 213.66
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Properties
- Melting point:
- 208-210°C
- Boiling point:
- 364.3±32.0 °C(Predicted)
- Density
- 1.2069 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- solubility
- 1 M HCl: 50 mg/mL
- form
- solid
- pka
- pKa 3.87±0.1(H2O) (Uncertain)
- color
- white to very faintly yellow
- Water Solubility
- Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6
- Merck
- 14,937
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
- InChIKey
- KPYSYYIEGFHWSV-UHFFFAOYSA-N
- SMILES
- C1(C=CC(Cl)=CC=1)C(CN)CC(=O)O
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P330+P331+P310
- Hazard Codes
- T,Xn
- Risk Statements
- 61-25-36/37/38-42/43-20/21/22
- Safety Statements
- 53-22-36/37/39-45-52-36-26
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- MW5084200
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2922492050
- Toxicity
- LD50 in male mice, rats (mg/kg): 45, 78 i.v.; 103, 115 s.c.; 200, 145 orally (Tadokoro)
Use
Baclofen is a γ-aminobutyric acid derivative. it is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. it take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord.
79 India supplier list of "Baclofen"
- Product Name:Baclofen
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Pune,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: NaviMumbai,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Baclofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA