Balofloxacin
Balofloxacin
- CAS:
- 127294-70-6
- MF:
- C20H24FN3O4
- MW:
- 389.42
Suppliers by country/region
Company Type
Properties
- Melting point:
- 137°C
- Boiling point:
- 608.3±55.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- H2O : < 0.1 mg/mL (insoluble)DMSO : 0.67 mg/mL (1.72 mM; Need ultrasonic)
- form
- Solid
- pka
- 6.44±0.50(Predicted)
- color
- White to off-white
- BRN
- 8362117
Safety Information
- Symbol(GHS)
GHS02
- Signal word
- Warning
- Hazard statements
- H228
- Precautionary statements
- P403-P501c
- WGK Germany
- 3
Use
Balofloxacin, a novel orally-active fluoroquinolone antibiotic, was introduced in South Korea for the treatment of urinary tract infections (UTI). It can be synthetized by reaction of 3-(methylamino)piperidine with the classical 4-quinolone-3-carboxylic acid template. In vitro antibacterial activity of balofloxacin against gram-positive bacteria (Staphylococcus aureus including methicillin-resistant S. aureus, Staphylococcus epidermis, Streptococcus pneumonia, Streptococcus pyrogenes) was almost equal to that of sparfloxacin or tosufloxacin, in contrast its activity against gram-negative bacteria was 2 times or more lower. In clinical trials, balofloxacin was well tolerated and showed comparable efficacy to ofloxacin in patients with UTls. After oral administration, balofloxacin was well absorbed, and was primarily eliminated unchanged in the urine with an elimination half-life of approximately 8 h. In animal studies, balofloxacin did not exhibit any phototoxicity.
6 India supplier list of "Balofloxacin"
![](/images/pro-3.jpg)
- Product Name:Balofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
![](/images/pro-3.jpg)
- Product Name:Balofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
![](/images/pro-3.jpg)
- Product Name:Balofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
![](/images/pro-3.jpg)
- Product Name:Balofloxacin
- Products Intro:Brand:pharmaffiliates | Product Number:PA021970000
- Company Type: Trader
- Country/Region: Haryana,INDIA
![](/images/pro-3.jpg)
- Product Name:Balofloxacin
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Balofloxacin
- Products Intro:Purity: USP, BP | Package: 1KG;|5KG;|25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Active Pharmaceuticals Ingredients,Peptide,Cosmetics,Nutritional supplements,Fine chemicals
$0.00-0.00 / 1KG