Bulaquine
Bulaquine
- CAS:
- 79781-00-3
- MF:
- C21H27N3O3
- MW:
- 369.46
Suppliers by country/region
Properties
- Boiling point:
- 616.7±55.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 5.60±0.20(Predicted)
Safety Information
Use
Bulaquine is a derivative of primaquine that was introduced in India in combination with chloroquine as a treatment against malaria. The compound is prepared by condensation of primaquine with 3-acetyl-y-butyrolactone in presence of a catalytic amount of base. Bulaquine kills the latent tissue stage (hypnozoites) of the parasite Plasmodium vivax accumulated in the liver and responsible for relapses. Its efficient anti-relapse activity was demonstrated against sporozoite induced Plasmodium cynomolgi infection in rhesus monkey. Bulaquine is safer than primaquine, the preceding candidate against malaria relapse. Although it is stable at pH 7-8, bulaquine is hydrolyzed to primaquine under acidic conditions.
1 India supplier list of "Bulaquine"
- Product Name:Bulaquine
- Products Intro:Brand:clearsynth | Product Number:CS-T-70072
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Bulaquine
- Company Type: Reagent
- Country/Region: Mallapur,INDIA
- Product Name:Bulaquine
- Products Intro:Package: 100 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Bulaquine
- Products Intro:Brand：aksci | Product Number：3419CR
- Company Type: Trader
- Country/Region: UNITED STATES
-
25mg$245.00
- Product Name:Bulaquine
- Products Intro:Brand:trc-canada | Product Number:B694880
- Company Type: Trader
- Country/Region: CANADA
- Product Name:compound 80-53
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:compound 80-53
- Company Type: Trader
- Country/Region: CHINA