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BUPRENORPHINE
BUPRENORPHINE
- CAS:
- 52485-79-7
- MF:
- C29H41NO4
- MW:
- 467.65
Properties
- Melting point:
- 260-262°C
- Boiling point:
- 570.1°C (rough estimate)
- Density
- 1.0953 (rough estimate)
- refractive index
- 1.6290 (estimate)
- Flash point:
- 9℃
- storage temp.
- -20°C
- solubility
- Very slightly soluble in water, freely soluble in acetone, soluble in methanol, slightly soluble in cyclohexane. It dissolves in dilute solutions of acids.
- pka
- pKa 8.24(H2O t=23.0±0.3) (Uncertain)
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H301+H311+H331-H370
- Precautionary statements
- P210-P260-P280-P301+P310-P311
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 16-36/37-45-7
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 1
- Toxicity
- LD50 oral in mouse: 260mg/kg
Use
Buprenorphine is used to treat dependence/addiction to opioids. Buprenorphine belongs to a class of drugs called mixed opioid agonist-antagonists. It helps prevent withdrawal symptoms caused by stopping other opioids.
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