Busulfan
Busulfan
- CAS:
- 55-98-1
- MF:
- C6H14O6S2
- MW:
- 246.3
Suppliers by country/region
Company Type
Properties
- Melting point:
- 114-117 °C(lit.)
- Boiling point:
- 359.3°C (rough estimate)
- Density
- 1.305 (estimate)
- refractive index
- 1.5630 (estimate)
- Flash point:
- 9℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Very slightly soluble in water, freely soluble in acetone and in acetonitrile, very slightly soluble in ethanol (96 per cent).
- form
- Crystalline Powder
- color
- Pale Brown
- Water Solubility
- Decomposes
- Merck
- 14,1505
- BRN
- 1791786
- Stability:
- Moisture Sensitive
- CAS DataBase Reference
- 55-98-1(CAS DataBase Reference)
- IARC
- 1 (Vol. 4, Sup 7, 100A) 2012
- EPA Substance Registry System
- Busulfan (55-98-1)
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H301-H340-H350-H360FD
- Precautionary statements
- P202-P264-P270-P280-P301+P310-P405
- Hazard Codes
- T+,T,F
- Risk Statements
- 45-26/27/28-63-46-36/37/38-23/24/25-39/23/24/25-11
- Safety Statements
- 53-36/37/39-45-28A-36/37-16-7
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- RTECS
- EK1750000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29053990
- Hazardous Substances Data
- 55-98-1(Hazardous Substances Data)
- Toxicity
- LD50 i.v. in rats: 1.8 mg/kg (Scherf)
Use
Busulfan is a cytotoxic alkylating chemotherapeutic agent that is extensively used as preparative conditioning regimen prior to allogeneic HSCT for hematologic malignancies. Busulfan has been widely used in the treatment of CML and other hematologic malignancies and myelodysplastic disorders. The principal effect of busulfan is myelosuppression and myeloablation when used at the recommended dosage. Currently, busulfan is indicated for use in combination with cyclophosphamide to destroy cancer cells and make room for new bone marrow to grow prior to a bone marrow or peripheral blood progenitor cell replacement procedure. As a component of a conditioning regimen for HSCT, busulfan also suppresses the immune system so that the patient does not reject the new bone marrow.
52 India supplier list of "Busulfan"
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: AndhraPradesh,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: AndhraPradesh,INDIA
- Product Name:Busulfan 1,4-Butanediol-dimethanesulfonate Esters; Busulphan
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Busulfan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: New Delhi,INDIA