Capecitabine
Capecitabine
- CAS:
- 154361-50-9
- MF:
- C15H22FN3O6
- MW:
- 359.35
Suppliers by country/region
Company Type
Properties
- Melting point:
- 110-121°C
- Density
- 1.49±0.1 g/cm3(Predicted)
- Flash point:
- 87℃
- storage temp.
- 2-8°C
- solubility
- H2O: soluble10mg/mL, clear (warmed)
- pka
- 5.41±0.40(Predicted)
- form
- powder
- color
- white to beige
- Merck
- 14,1754
- InChIKey
- GAGWJHPBXLXJQN-UORFTKCHSA-N
- SMILES
- C[C@H]1O[C@@H](N2C=C(F)C(NC(OCCCCC)=O)=NC2=O)[C@H](O)[C@@H]1O
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H341-H350-H360FD
- Precautionary statements
- P201-P308+P313
- Hazard Codes
- T
- Risk Statements
- 45-60-61-68
- Safety Statements
- 53-22-36/37-45
- WGK Germany
- 3
- RTECS
- HA3852500
- HS Code
- 29349990
Use
Capecitabine is a new form of oral fluorinated pyrimidine drug. Capecitabine was developed by Roche Pharmaceuticals, and its commercial name is Xeloda. Capecitabine can change in vivo into 5- FU, an anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate drug that targets cancer cells to inhibit cell division and disrupt RNA and protein synthesis. Its effects are significantly tied to the level of TP enzyme expression in neoplastic tissue and to DPD enzyme in vivo expression. It is suitable as further treatment for advanced primary or metastatic breast cancer patients who have not responded to paclitaxel or anthracycline antibiotics. As an anticancer drug, it is mostly used to treat advanced primary or metastatic breast cancer, as well as in treatment for non-small cell lung cancer, pancreatic cancer, bladder cancer, rectal cancer, colon cancer, gastric cancer, and other solid tumors. Many drugs such as taxanes (paclitaxel, docetaxel, mitomycin, cisplatin, etc.) can increase TP enzyme expression in neoplastic tissues and also have curative effects on gastric cancer. When used in combination with Capecitabine, these drugs can also improve Capecitabines anticancer abilities and produce synergistic effects.
140 India supplier list of "Capecitabine"
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Pune,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:CapacitabineAPI&intermediates
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Capecitabine
- Products Intro:Purity: 97% | Package: 50 MG; 100 MG; 250 MG ; 500 mg
- Company Type: Manufacturer
- Country/Region: Bangalore,INDIA