Cimetidine manufacturers and suppliers in india

Cimetidine

Properties

Melting point:: 139-144°C

Boiling point:: 476.2±55.0 °C(Predicted)

Density: 1.2583 (rough estimate)

refractive index: 1.5700 (estimate)

storage temp.: 2-8°C

solubility: Slightly soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute mineral acids.

form: Solid

pka: pKa 6.80 (Uncertain)

color: White to Off-White

Water Solubility: 0.5 g/100 mL at 20 ºC

Merck: 14,2279

InChIKey: AQIXAKUUQRKLND-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H303-H360

Precautionary statements: P202-P405-P501a-P201-P280-P308+P313

Hazard Codes: T,Xn

Risk Statements: 60-42/43-36/37/38-20/22

Safety Statements: 53-26-36/37/39-45-36-22

WGK Germany: 3

RTECS: MF0035500

HS Code: 29339900

Toxicity: LD50 in mice, rats (mg/kg): 2600, 5000 orally; 150, 106 i.v.; 470, 650 i.p. (Brimblecombe)

Use

This drug contains cimetidine hence one should not ingest Tagamet HB if they are hypersensitive to the drug or its constituents. Cimetidine should be kept out of reach of children. Cimetidine is an antiandrogen hence it may result in sexual dysfunction and feminization in men. The drug is considered safe for use amongst pregnant women, but since it can be absorbed into breast milk, lactating mothers should refrain from Cimetidine. People with kidney or liver disease may be at a higher risk of experiencing intense side effects if Cimetidine is administered without appropriate advice from a medical practitioner. The doctor should indicate how the drug may influence the pre-existing liver or kidney disease, and whether the patient may require additional monitoring.