Colchicine
Colchicine
- CAS:
- 64-86-8
- MF:
- C22H25NO6
- MW:
- 399.44
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Properties
- Melting point:
- 150-160 °C (dec.)(lit.)
- alpha
- -250 º (c=1, alcohol)
- Boiling point:
- 522.37°C (rough estimate)
- Density
- 1.2770 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: 10 mg/mL
- pka
- 12.36(at 20℃)
- form
- powder
- color
- white to yellow with a green cast
- Water Solubility
- 45 g/L (20 ºC)
- Sensitive
- Light Sensitive
- Merck
- 14,2471
- BRN
- 2228813
- BCS Class
- 3
- Stability:
- Stable. Light sensitive. Incompatible with strong oxidizing agents.
- InChIKey
- IAKHMKGGTNLKSZ-INIZCTEOSA-N
- LogP
- 1.300
- CAS DataBase Reference
- 64-86-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Colchicine(64-86-8)
- EPA Substance Registry System
- Colchicine (64-86-8)
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H300-H340
- Precautionary statements
- P202-P264-P270-P280-P301+P310-P405
- Hazard Codes
- T+,T,Xi
- Risk Statements
- 26/28-41-46
- Safety Statements
- 13-45-36/37/39-28-26-53
- RIDADR
- UN 1544 6.1/PG 1
- WGK Germany
- 3
- RTECS
- GH0700000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- I
- HS Code
- 29399990
- Hazardous Substances Data
- 64-86-8(Hazardous Substances Data)
- Toxicity
- LD50 in rats (mg/kg): 1.6 i.v. (Rosenbloom, Ferguson); in mice (mg/kg): 4.13 i.v. (Beliles)
Use
Colchicine is present in the poisonous autumncrocus (meadow saffron). It is the major alkaloid of Colchicum autumnale L. and Liliaceae. It was used in poison potions in theancient kingdom of Colchis (Greece). It isused therapeutically as an antineoplast, for thesuppression of gout, and in the treatment ofMediterranean fever. It is used in plant studiesfor doubling chromosome groups.
143 India supplier list of "Colchicine"
- Product Name:Colchicine, 95%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Madhya Pradesh,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: NaviMumbai,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Colchicine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA