Creatine manufacturers and suppliers in india

Creatine

Properties

Melting point:: ~295 °C (dec.)

Boiling point:: 242.43°C (rough estimate)

Density: 1,33 g/cm³

refractive index: 1.5700 (estimate)

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

solubility: Water (Slightly, Heated)

pka: 2.63(at 25℃)

form: Solid

color: White to Off-White

Water Solubility: Soluble in water.

Merck: 14,2568

BRN: 907175

InChIKey: CVSVTCORWBXHQV-UHFFFAOYSA-N

LogP: -1.258 (est)

CAS DataBase Reference: 57-00-1(CAS DataBase Reference)

NIST Chemistry Reference: Glycine, N-(aminoiminomethyl)-N-methyl-(57-00-1)

EPA Substance Registry System: Glycine, N-(aminoiminomethyl)-N-methyl- (57-00-1)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36

WGK Germany: 3

TSCA: Yes

HS Code: 29252900

Hazardous Substances Data: 57-00-1(Hazardous Substances Data)

Toxicity: A compound that is phosphorylated to phosphocreatine, which represents a store of high-energy phosphoryl groups in muscle that can be transferred to ADP, yielding ATP for muscle contraction. The enzyme involved in phosphate transfer between them is creatine phosphokinase that catalyzes the reaction Phosphocreatine+ADP→ATP+creatine An increase in serum creatine phosphokinase may be indicative of damage to non-hepatic tissue but not to the liver.

Use

Creatine is a kind of natural nutrients in presented in the human body and can also be synthesize through arginine, glycine, and methionine in the liver, kidney and pancreas: in the presence of the catalysis of the arginine/glycine transamidinase in the kidney, the amidino group of the arginine can be transferred to the amino group of the glycine, generating glycocyamine. Then in the liver, with the catalysis of the glycocyamine methyltransferase, the methyl group of the S-adenosylmethionine can be transferred to the glycocyamine, generating creatine; it can increase the water content of the muscle cells, help the muscle cells to store energy, increase the protein synthesis and some other fundamental functions; wherein the artificially synthetic creatine can be used as the nutritional supplements for promoting the adaptation of skeletal muscle on fierce exercise and fighting against the excessive fatigue of individual in weakness; it can also be used for making the drugs for the treatment of heart disease and respiratory insufficiency; it can be used for making the pharmaceutical formulation containing human growth hormones; it can be applied to the compound health food, with anti-aging and physical power-recovering effect.