Duloxetine hydrochloride
Duloxetine hydrochloride
- CAS:
- 136434-34-9
- MF:
- C18H20ClNOS
- MW:
- 333.88
Suppliers by country/region
- India(136)
- CHINA(262)
- United States(51)
- Canada(12)
- United Kingdom(19)
- Germany(8)
- Europe(3)
- Japan(4)
- South Korea(9)
- Israel(1)
- Colombia(1)
- Spain(6)
- The Netherlands(1)
- Slovakia(2)
- Mexico(2)
- Greece(1)
- Italy(1)
- Brazil(1)
- United Arab Emirates(1)
- Czech Republic(1)
- France(1)
- Nepal(1)
- Slovenia(1)
- South Africa(1)
Company Type
Properties
- Melting point:
- 118-122°C
- Flash point:
- 9℃
- storage temp.
- room temp
- solubility
- H2O: soluble5mg/mL (clear solution, warmed)
- pka
- pKa in DMF-water (66:34): 9.6(at 25℃)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +116 to +125°, c = 1 in methanol
- Merck
- 14,3465
- InChI
- InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
- InChIKey
- BFFSMCNJSOPUAY-VOPAOICTNA-N
- SMILES
- C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xi,Xn,T,F
- Risk Statements
- 36/37/38-22-39/23/24/25-23/24/25-11
- Safety Statements
- 26-36/37-45-16-7
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 3
- RTECS
- XN0258000
- HS Code
- 29349990
Use
Duloxetine Hydrochloride acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate. Duloxetine hydrochloride is a new kind of selective dual inhibitor of 5 hydroxy trptamine (5-ht) and norepinephrine reuptake, and thus having antidepressant effect, while also having inhibitory effect on the central pain. its pharmacological characteristic is being able to inhibit neuronal pre-synaptic membrane’s reuptake on 5-hydroxy trptamine and norepinephrine but instead have a low inhibitory effect on the reuptake of dopamine.
136 India supplier list of "Duloxetine hydrochloride"
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Duloxetine hydrochloride
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA