Eflornithine
Eflornithine
- CAS:
- 67037-37-0
- MF:
- C6H12F2N2O2
- MW:
- 182.17
Suppliers by country/region
Company Type
Properties
- Density
- 1.1800 (estimate)
- storage temp.
- -15°C
Safety Information
Use
Eflornithine is used for the treatment of West African sleepingsickness, caused by Trypanosoma brucei gambiense.It is specifically indicated for the meningoencephaliticstage of the disease. Eflornithine is a myelosuppressivedrug that causes high incidences of anemia, leukopenia,and thrombocytopenia. Complete blood cell counts must bemonitored during the course of therapy.The irreversible inactivation of ornithine decarboxylaseby eflornithine is accompanied by decarboxylation andrelease of fluoride ion from the inhibitor, suggesting enzyme-catalyzed activation of the inhibitor. Only the (—) isomer,stereochemically related to L-ornithine, is active.Eflornithine is supplied as the hydrochloride salt. It may beadministered either intravenously or orally. Approximately80% of the unchanged drug is excreted in the urine.Penetration of eflornithine into the CSF is facilitated by inflammationof the meninges.
3 India supplier list of "Eflornithine"
- Product Name:Eflornithine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Eflornithine
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Eflornithine
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:eflornithine
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Eflornithine USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Eflornithine
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Wholesale price
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Eflornithine
- Company Type: Manufacturer
- Country/Region: CHINA
- Product Name:Eflornithine
- Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Palmitoylethanolamide,GHK-Cu,Copper tripeptide-1,Nicotinamide Riboside Chloride,NMN,Ergothioneine
- Products Intro:Brand：1pchem | Product Number：1P01JGKZ
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:H-DL-(a-difluoromethyl)Orn-OH
- Products Intro:Brand：ChemShuttle
- Company Type: Trader
- Country/Region: UNITED STATES