EPZ015666
EPZ015666
- CAS:
- 1616391-65-1
- MF:
- C20H25N5O3
- MW:
- 383.44
Suppliers by country/region
Company Type
Properties
- Melting point:
- 124-131°C
- Boiling point:
- 686.4±55.0 °C(Predicted)
- Density
- 1.331±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO (up to 20 mg/ml)
- pka
- 12.40±0.46(Predicted)
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
Use
EPZ015666 (GSK3235025) is an orally available inhibitor of protein arginine methyltransferase-5 (PRMT5), which is involved in diverse cellular processes, including tumorigenesis, and its overexpression is observed in cell lines and primary patient samples derived from lymphomas, particularly mantle cell lymphoma (MCL).EPZ015666 showed dose-dependent antitumor activity in multiplein vitroandin vivomantle cell lymphoma (MCL) models with treatment of MCL cell lines leading to inhibition of SmD3 methylation and cell death. Therefore, it is a potential drug candidate for future cancer therapy.
1 India supplier list of "EPZ015666"
- Product Name:EPZ015666
- Products Intro:Brand:sigma aldrich | Product Number:SML1421 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:EPZ015666 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089250
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:EPZ015666
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:EPZ015666
- Products Intro:Purity: >98% | Package: 300mg | CustNote: BOC Sciences also provides custom synthesis services for EPZ015666.
- Company Type: Trader
- Country/Region: UNITED STATES
-
1g$1
- Product Name:EPZ 015666
- Products Intro:Purity: 0.99， AD68|Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:EPZ015666
- Products Intro:Purity: 0.98 | Package: mg,gram,kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API,Dye Intermediate,Customized products,Peptide,Curing agent
- Product Name:EPZ015666
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:EPZ015666
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
- Product Name:EPZ015666
- Products Intro:Purity: 98% | Package: 25mg, 10mg, 2mg, 5mg, 1mg, 50mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:EPZ015666
- Products Intro:Purity: 98% (HPLC) | Package: $107.9/5mg;$486.9/25mg;$489.9/50mg;$706.9/100mg;Bulk package | CustNote: 98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies