Esomeprazole magnesium trihydrate manufacturers and suppliers in india

Esomeprazole magnesium trihydrate

Properties

Melting point:: 184-189°C (dec.)

storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility: Slightly soluble in water, soluble in methanol, practically insoluble in heptane.

form: Solid

color: White to off-white

InChI: InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;

InChIKey: VEVZQDGATGBLIC-UHFFFAOYSA-N

SMILES: C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 22

WGK Germany: 3

HS Code: 2933399090

Use

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy. Zollinger-Ellison syndrome Peptic ulcer, site unspecified Duodenal ulcer Gastric ulcer Gastro-oesophageal reflux disease Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications: Gastro-Oesophageal Reflux Disease (GORD): treatment of erosive reflux oesophagitis; long-term management of patients with healed oesophagitis to prevent relapse; symptomatic treatment of gastro-oesophageal reflux disease (GORD). In combination with appropriate antibiotics for: healing of duodenal ulcer associated with Helicobacter pylori; eradication of Helicobacter pylori in patients with active or healed peptic ulcer. Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy. Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy. Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

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Esomeprazole magnesium trihydrate