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Ezetimibe

Ezetimibe

CAS:
163222-33-1
MF:
C24H21F2NO3
MW:
409.43

Properties

Melting point:
164-166°C
alpha 
D22 -33.9° (c = 3 in methanol)
Boiling point:
654.9±55.0 °C(Predicted)
Density 
1.334±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)
pka
9.72±0.30(Predicted)
form 
powder
color 
White or off-white
BCS Class
2
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI
InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey
OLNTVTPDXPETLC-XPWALMASSA-N
SMILES
N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O

Safety Information

Symbol(GHS) 

GHS09
Signal word 
Warning
Hazard statements 
H410
Precautionary statements 
P273-P391-P501
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
HS Code 
29337900

Use

Ezetimibe was approved as the first hypolipidemic drug to act by blocking the absorption of dietary cholesterol. Ezetimibe is indicated as monotherapy or in combination with an HMGRI for the reduction of elevated total cholesterol, LDL cholesterol, and apoB in patients with primary (heterozygous familial and nonfamilial) hypercholesterolemia.

48 India supplier list of "Ezetimibe"

  • Product Name:Ezetimibe
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 25mg, 50mg,100mg,200mg
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Ezetimibe
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA

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