Fluorescein isothiocyanate isomer I manufacturers and suppliers in india

Fluorescein isothiocyanate isomer I

Properties

Melting point:: >360 °C(lit.)

Boiling point:: 708.6±60.0 °C(Predicted)

Density: 1.3423 (rough estimate)

refractive index: 1.5060 (estimate)

storage temp.: 2-8°C

solubility: Slightly soluble in DMSO, ethanol, methanol DMF and acetone

form: powder

pka: 2.2, 4.4, 6.7(at 25℃)

color: White

PH Range: Weak green uorescence (6.0) to strong green uorescence (7.2)

Water Solubility: practically insoluble

Sensitive: Moisture Sensitive

λmax: 490nm

BRN: 1407295

Stability:: Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.

Major Application: Magnetic nanowires, immunoassays, analyzing proteins, identifying chromosomes, Salmonella mosomes, diagnosis of cancer, kidney diseases, detecting pathogens, genes, Salmonella cells, toxoplasmosis, enzyme-mediated nucleic acid cleavage, surface molecules on colorectal cancers, treating cancer, chronic lymphocytic leukemia

Biological Applications: Analyzing sugar chain; detecting iodide/iodate or total iodine; detecting/imaging thiols; detecting/quantifying biotin derivatives;16 diagnosing classical Hodgkin lymphoma (CHL) in lymph nodes; cellulose nanocrystals for bioimaging applications; treating neuroinflammation; treating/diagnosing cancer; PEO-PCL-PEO triblock copolymers for topical delivery; polymersomes in biomedical or cosmetic applications;apoptosis assay; as a substrate for measuring heparanase activity, human immunodeficiency virus (HIV-1) proteinase activity, kinase activity, phosphatase activity, β-lactamase activity, transglutaminase (TG2) activity; implantable drug-delivery devicess

InChIKey: MHMNJMPURVTYEJ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H317-H334

Precautionary statements: P261-P272-P280-P284-P302+P352-P333+P313

Hazard Codes: Xn,Xi

Risk Statements: 42/43-36/37/38-22

Safety Statements: 22-45-36/37/39-26-36/37-36

WGK Germany: 3

F: 10

TSCA: Yes

HS Code: 29329990

Use

Fluorescein -5-isothiocyanate is a kind of fluorescent marker for biochemical applications. Reacts under mild conditions with primary amines and it is also used in modification of actin at lys-61, labelling of FAB and the modification of thiol groups.