garcinol
garcinol
- CAS:
- 78824-30-3
- MF:
- C38H50O6
- MW:
- 602.8
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Properties
- Melting point:
- 132 °C
- Boiling point:
- 710.8±60.0 °C(Predicted)
- Density
- 1.114±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
- pka
- 4.50±1.00(Predicted)
- form
- Yellow solid.
- color
- Yellow
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.
- LogP
- 11.546 (est)
Safety Information
Use
Garcinol is an inhibitor of the histone acetyltransferases (HATs) p300 and PCAF (IC50 = 7 and 5 μM, respectively). It also inhibits the HAT GCN5 in Cryptococcus neoformans, inducing temperature sensitivity and impairing growth. A polyisoprenylated benzophenone isolated from Garcinia indica, garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions.
0 India supplier list of "garcinol"
$1.00/ 1g
- Product Name:Garcinol
- Products Intro:Purity: 95-99% | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
-
10 mg$139.00
- Product Name:(1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione
- Products Intro:Brand: Tocris Bioscience | Product Number: 4827 | Purity: ≥98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED KINGDOM