GDC-0068
GDC-0068
- CAS:
- 1001264-89-6
- MF:
- C24H32ClN5O2
- MW:
- 458
Suppliers by country/region
Company Type
Properties
- Melting point:
- >106°C (dec.)
- Boiling point:
- 669.4±55.0 °C(Predicted)
- Density
- 1.254
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- Soluble in DMSO.
- pka
- 13.11±0.40(Predicted)
- form
- Solid
- color
- peachy
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Use
DC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50 of 5 nM, 18 nM, and 8 nM, respectively.GDC-0068 is a highly selective AKT inhibitor targeting Akt1 , Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.
2 India supplier list of "GDC-0068"
- Product Name:GDC-0068 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089880
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:GDC-0068
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone
- Products Intro:Brand:pharmaffiliates | Product Number:PA090940000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:GDC-0068
- Products Intro:Brand:ajchemicals | Product Number:JDH-30599 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:GDC-0068
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Ipatasertib
- Products Intro:Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for Ipatasertib.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:GDC-0068
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:Ipatasertib
- Products Intro:Purity: 0.98 | Package: 25g;1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Bredereck's Reagent,Salicylic Acid,Amino Acids,Bipyridine Derivatives,Phenanthroline Derivatives
- Product Name:GDC-0068
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA