Hydrochlorothiazide
Hydrochlorothiazide
- CAS:
- 58-93-5
- MF:
- C7H8ClN3O4S2
- MW:
- 297.74
Suppliers by country/region
- India(115)
- Singapore(1)
- China(210)
- United States(52)
- United Kingdom(21)
- Russia(1)
- Canada(4)
- Germany(15)
- Europe(1)
- The Netherlands(3)
- Switzerland(3)
- Belgium(3)
- South Korea(7)
- Indonesia(1)
- Philippines(1)
- Poland(4)
- Israel(2)
- Slovenia(1)
- Brazil(5)
- Japan(1)
- France(5)
- Egypt(3)
- Venezuela(1)
- Italy(2)
- Czech Republic(1)
- Malaysia(1)
- Nepal(1)
- Spain(2)
- United Arab Emirates(1)
- Mexico(1)
- Austria(1)
- Nigeria(1)
- Greece(1)
Company Type
Properties
- Melting point:
- 273 °C
- Boiling point:
- 577.0±60.0 °C(Predicted)
- Density
- 1.6761 (rough estimate)
- refractive index
- 1.6100 (estimate)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- Very slightly soluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides
- pka
- 7.9, 9.2(at 25℃)
- form
- solid
- color
- White to Off-White
- Odor
- wh. or pract. wh. cryst. powd., odorless
- Water Solubility
- 722mg/L(25 ºC)
- λmax
- 318nm(H2O)(lit.)
- Merck
- 14,4781
- BRN
- 625101
- BCS Class
- 3,4
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- JZUFKLXOESDKRF-UHFFFAOYSA-N
- LogP
- -0.070
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xi,T,F,Xn
- Risk Statements
- 22-42/43-36/38-23/25-36/37/38-39/23/24/25-23/24/25-11
- Safety Statements
- 22-24-36/37-45-33-16-7-36/37/39-27-26
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 2
- RTECS
- DK9100000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29350090
- Toxicity
- LD50 in mice (mg/kg): 590 i.v.; >8000 orally (Piala)
Use
Hydrochlorothiazide is a kind of thiazide diuretic drugs with moderate diuretic effect. It exert is diuretic effect through acting on the medullary ascending limb cortical segment, inhibiting the active re-absorption of Cl-and passive absorption of Na+ at this site. In addition, the product also has a hypotensive effect and anti-diuretic effect. It is suitable for treating a variety of edema, particularly for cardiogenic edema. It can also be used as antihypertensive agents, for treatment light, medium hypertension. It also has certain efficacy in treating diabetes insipidus, and idiopathic hypercalciuria. Commonly used thiazide diuretics include hydrochlorothiazide, chlorthalidone, indapamide and the like.
115 India supplier list of "Hydrochlorothiazide"
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:4-Amino-6-Chloro 1, 3 Benzene Disulphonamide
- Products Intro:Purity: 99%
- Company Type: Manufacturer
- Country/Region: Ahmedabad,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Hydrochlorothiazide 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Hydrochlorothiazide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA