JAK3 INHIBITOR I
JAK3 INHIBITOR I
- CAS:
- 202475-60-3
- MF:
- C16H15N3O3
- MW:
- 297.31
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Company Type
Properties
- Boiling point:
- 468.1±40.0 °C(Predicted)
- Density
- 1.336±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO: 18 mg/mL, soluble
- form
- solid
- pka
- 10.06±0.26(Predicted)
- color
- yellow
- Stability:
- Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
Use
Janex 1 is a Janus tyrosine kinase 3 (JAK3) inhibitor. Inhibition of JAK3 has been shown to exhibit protective action against the development of T1D in non-obese diabetic (NOD) mice. Janex 1 has been shown to suppresses proliferation of short-term cultured NOD CD4+ T cells through induction of apoptosis, while promoting survival of a particular population of long-term cultured cells. It ameliorates the expression of TNF-α-induced cell adhesion molecules and improves myocardial vascular permeability.
0 India supplier list of "JAK3 INHIBITOR I"
- Product Name:JAK3InhibitorI-CAS202475-60-3-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:420101 | Purity:TheJAK3InhibitorI,alsoreferencedunderCAS202475-60-3,controlsthebiologicalactivit
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Janex-1
- Products Intro:Brand:ajchemicals | Product Number:JDH-83607 | Purity:95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Janex1
- Products Intro:Brand:clearsynth | Product Number:CS-T-30164
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:WHI-P131
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:4-(4'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00/ 1KG
- Product Name:JANEX-1
- Products Intro:Purity: >98% | Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for JANEX-1.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenol
- Products Intro:Purity: 0.95_) | Package: 10G;50G;100G | CustNote: Chemically Pure
- Company Type: Trader
- Country/Region: CHINA
- Product Name:JANEX-1
- Products Intro:Purity: 98% | Package: $240.9/5mg;$411.9/10mg;$1373.9/50mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:JANEX-1
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A925799
- Company Type: Reagent
- Country/Region: CHINA
-
5MG$209.00
- Product Name:JAK3InhibitorI-CAS202475-60-3-Calbiochem
- Products Intro:Brand:Sigma-Aldrich | Product Number:420101 | Purity:TheJAK3InhibitorI,alsoreferencedunderCAS202475-60-3,controls
- Company Type: Trader
- Country/Region: UNITED STATES