KIGAMICIN C
KIGAMICIN C
- CAS:
- 680571-51-1
- MF:
- C41H47NO16
- MW:
- 809.81
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Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- Yellow powder.
Safety Information
Use
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
0 India supplier list of "KIGAMICIN C"
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0.5MG$425.00
- Product Name:KIGAMICIN C
- Products Intro:Brand:Acccorporation | OriginalID:PXT0003487 | Purity:95.00%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Kigamicin C
- Products Intro:Brand:Usbio | OriginalID:453048
- Company Type: Trader
- Country/Region: UNITED STATES