Kinetin manufacturers and suppliers in india

Kinetin

Properties

Melting point:: 269-271 °C (dec.)(lit.)

Boiling point:: 355.49°C (rough estimate)

Density: 1.2639 (rough estimate)

refractive index: 1.7610 (estimate)

Flash point:: 269-271°C

storage temp.: -70°C

solubility: H₂O: soluble

form: crystalline

pka: pKa1 2.7; pKa2 9.9(at 25℃)

color: white

Water Solubility: Soluble in water (<1 mg/ml) at 25°C, Acetic acid (49.00-51.00 mg/ml), DMSO (43 mg/ml) at 25°C, ethanol (<1 mg/ml) at 25°C, 0.1 N Sodium hydroxide (1% w/v), methanol (slightly), and dilute aqueous hydrochloric acid or sodium hydroxide (freely).

Decomposition: 269-271 ºC

Merck: 14,5311

BRN: 21703

InChIKey: QANMHLXAZMSUEX-UHFFFAOYSA-N

LogP: 1.200 (est)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P280

Hazard Codes: Xi

Risk Statements: 68-36/37/38

Safety Statements: 23-24/25-22-36/37/39-27-26

WGK Germany: 3

RTECS: AU6270000

Hazard Note: Irritant

TSCA: Yes

HS Code: 29349990

Toxicity: LD50 intraperitoneal in mouse: 450mg/kg

Use

Kinetin (or Vivakin) was introduced as Kinerase in the US as a new ingredient for the treatment of age related photodamage of skin. This 6- furfurylaminopurine is a synthetic cytokinin, a family of plant growth factors, and was shown to be a highly potent growth factor. In vitro, it was able to delay or prevent the onset of age-related changes in skin cells without affecting cellular lifespan. In a double-blind clinical trial, Kinetin (0.005%) partially reversed the clinical signs of photodamaged skin and demonstrated a good safety profile. It could have potential in psoriasis as well as in other proliferative skin disorders.