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Lapatinib

Lapatinib

CAS:
231277-92-2
MF:
C29H26ClFN4O4S
MW:
581.06

Properties

Melting point:
144-146oC
Boiling point:
750.7±60.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
Soluble in DMSO (up to 200 mg/ml)
form 
solid
pka
6.34±0.19(Predicted)
color 
Yellow
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey
BCFGMOOMADDAQU-UHFFFAOYSA-N
SMILES
N1=C2C(C=C(C3=CC=C(CNCCS(C)(=O)=O)O3)C=C2)=C(NC2=CC=C(OCC3=CC=CC(F)=C3)C(Cl)=C2)N=C1

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H319-H362-H413
Precautionary statements 
P201-P260-P263-P273-P305+P351+P338-P308+P313
HS Code 
29349990

Use

Lapatinib, a new member of the 4-anilinoquinazoline class of rtk inhibitors (rtkis), was launched as an oral treatment for breast cancer. lapatinib has dual affinity for egfr and her2 tyrosine kinases. it is indicated in combination with capecitabine for treating patients with advanced or metastatic breast cancer whose tumors overexpress her2 and who have received prior therapy including an anthracycline, a taxane, and trastuzumab.

24 India supplier list of "Lapatinib"

  • Product Name:Lapatinib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Haryana,INDIA
  • Product Name:Lapatinib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Lapatinib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Lapatinib di tosylate
  • Products Intro:Purity: 98% | Package: 25KG;INR
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Lapatinib
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA
  • Product Name:Lapatinib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA
  • Product Name:Lapatinib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Ahmedabad,INDIA
  • Product Name:Lapatinib 95.00%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.073869
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Lapatinib
  • Products Intro:Brand:synzeal | Product Number:121745287
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Lapatinib
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA

Lapatinib Related Search:

NilotinibAnisole4-MethoxyphenylacetoneTeniposideNizatidineDiphenyl etherMethoxydiethylborane(Trifluoromethoxy)benzeneSunitinibGefitinibp-(2-Methoxyethyl) phenolImatinibImatinib mesylateLapatinib ditosylateDifluorochloromethanePhenylacetic acid2-Aminoethylmethylsulfone hydrochlorideN-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
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