Nilotinib
Nilotinib
- CAS:
- 641571-10-0
- MF:
- C28H22F3N7O
- MW:
- 529.52
Suppliers by country/region
Company Type
Properties
- Melting point:
- 231-233 °C
- Density
- 1.36
- storage temp.
- -20°C Freezer
- solubility
- Soluble in DMSO (up to 50 mg/ml)
- form
- Beige powder.
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChIKey
- HHZIURLSWUIHRB-UHFFFAOYSA-N
- SMILES
- N1(C=C(C)N=C1)C1C=C(C=C(C=1)NC(=O)C1C=CC(C)=C(NC2=NC=CC(C3=CC=CN=C3)=N2)C=1)C(F)(F)F
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- HS Code
- 29335990
Use
Nilotinib, an orally active signal transduction inhibitor that selectively inhibits the tyrosine kinase Bcr-Abl, was discovered and developed by Norvartis and was launched for the treatment of chronic myeloid leukemia (CML) in patients with Philadelphia chromosome-positive (Ph+) disease who are resistant or intolerant to imatinib mesilate. Additional clinical trials are currently underway for the treatment of acute lymphoblastic leukemia (ALL) and gastrointestinal stromal tumors (GISTs).
23 India supplier list of "Nilotinib"
- Product Name:Nilotinib
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl) phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl] amino] benzamide
- Products Intro:Purity: 99%
- Company Type: Manufacturer
- Country/Region: Ahmedabad,INDIA
- Product Name:Nilotinib
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:4-Methyl-N-[3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl) Phenyl]-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl] Amino] Benzamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Nilotinib
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Nilotinib 98%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.134672
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Nilotinib
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Nilotinib
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Nilotinib
- Products Intro:Brand:clearsynth | Product Number:CS-O-01983
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Nilotinib
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA