Loteprednol etabonate
Loteprednol etabonate
- CAS:
- 82034-46-6
- MF:
- C24H31ClO7
- MW:
- 466.95
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Company Type
Properties
- Melting point:
- 220.5-223.5
- Boiling point:
- 600.1±55.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble5mg/mL, clear (warmed)
- form
- powder
- pka
- 14.06±0.70(Predicted)
- color
- white to beige
- Water Solubility
- <1mg/L(23 ºC)
- Stability:
- Hygroscopic
- InChIKey
- DMKSVUSAATWOCU-ICASLIHPSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361-H413
- Precautionary statements
- P501-P273-P202-P201-P280-P308+P313-P405
- WGK Germany
- 3
- HS Code
- 2937.22.0000
Use
Loteprednol (as Loteprednol Etabonate) is a topical anti-inflammatory corticosteroid. Loteprednol etabonate (LE) has a 17-chloromethyl ester, in lieu of a ketone group, and a 17-etabonate group. LE is highly lipophilic and binds with high affinity to the glucocorticoid receptor. Any unbound LE is metabolized to inactive metabolites. Loteprednol etabonate is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitis. It is used in ophthalmic ointment for the treatment of post-operative inflammation and pain following ocular surgery. As a nasal spray, it is used for the treatment and management of seasonal allergic rhinitis.
51 India supplier list of "Loteprednol etabonate"
- Product Name:LOTEPREDNOL ETABONATE
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Loteprednol Etabonate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:loteprednol etabonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA