Mesotrione manufacturers and suppliers in india

Mesotrione

Properties

Melting point:: 165°

Boiling point:: 643.3±55.0 °C(Predicted)

Density: 1.474±0.06 g/cm3(Predicted)

storage temp.: Inert atmosphere,Room Temperature

solubility: Chloroform (Slightly), Methanol (Slightly, Heated)

pka: pKa (20°): 3.12

form: Solid

color: White to off-white

BRN: 8999656

InChIKey: KPUREKXXPHOJQT-UHFFFAOYSA-N

LogP: -0.700 (est)

Safety Information

Symbol(GHS): GHS08,GHS09

Signal word: Warning

Hazard statements: H361d-H373-H410

Precautionary statements: P202-P260-P273-P280-P308+P313-P391

Hazard Codes: N

Risk Statements: 50/53

Safety Statements: 60-61

RIDADR: UN 3077

WGK Germany: 2

Toxicity: LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >5 by inhalation; LC50 (96 hr) in bluegill sunfish, rainbow trout (mg/l): >120, >120

Use

Studies indicate that the toxic influence of the compound can be attributed to high plasma concentration levels of tyrosine which is resultant of inhibition by 4-hydroxyphenylpyruvate dioxygenase (HPPD). HPPD is an essential constituent of the biochemical route that aids the conversion of tyrosine to alpha-tocopherol and plastoquino\ne. Mesotrione is a highly potent agonist of HPPD against Arabidopsis thaliana, which is indicated by the Ki figure of c 6-18 pM. It is readily absorbed by weed species after foliar application and it is widely distributed to various parts of the plant through basipetal and acropetal movement. Maize crops are generally tolerant to Mesotrione as a result of selective metabolism by the plant. The compound may take a relatively long time to be absorbed in some weed species hence Mesotrione is applied as a selective herbicide in maize plantations. The plasma half-life of the compound is approximately 1 hour.