Miglitol manufacturers and suppliers in india

Miglitol

Properties

Melting point:: 114°C

Boiling point:: 453.7±45.0 °C(Predicted)

Density: 1.458±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).

form: solid

pka: 5.9(at 25℃)

color: White

Water Solubility: Soluble

Merck: 14,6187

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

InChIKey: IBAQFPQHRJAVAV-ULAWRXDQSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319

Precautionary statements: P305+P351+P338

WGK Germany: 3

RTECS: TN4350170

HS Code: 29333990

Use

Miglitol was introduced in Germany as an auxiliary treatment for non-insulin dependent diabetes (NIDDM). A simple two-step synthesis of Miglitol consists of converting 6-desoxy-6-aminosorbose into desoxynojirimycin by reductive cyclization, then selectively hydroxyethylating the cyclic nitrogen. Miglitol is a short-acting intestinal alpha-D-glucosidase inhibitor, reducing postprandial glucose excursions by helping to delay absorption of complex carbohydrates. Acarbose and voglibose are the previous compounds marketed in this class. At low doses, orally administered miglitol was shown to be rapidly and completely absorbed then removed by renal excretion.