MITHRAMYCIN A
MITHRAMYCIN A
- CAS:
- 18378-89-7
- MF:
- C52H76O24
- MW:
- 1085.15
Suppliers by country/region
Company Type
Properties
- Melting point:
- 180-183 °C
- alpha
- D20 -51° (c = 0.4 in ethanol)
- Boiling point:
- 761.72°C (rough estimate)
- Density
- 1.1576 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
- form
- Powder
- pka
- 4.54±0.60(Predicted)
- color
- Red to brown
- Merck
- 13,7619
- BRN
- 5236667
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn,T+
- Risk Statements
- 22-26/27/28
- Safety Statements
- 45-38-36/37/39-28A-22
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- PZ2800000
- F
- 10
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29419090
- Toxicity
- LD50 in mice, rats (mg/kg): 2.14, 1.74 i.v. (Slavik, Carter)
Use
Mithramycin A was the first of the aureolic acid class of antitumor antibiotics, isolated from Streptomyces. Mithramycin inhibits transcription and protein synthesis by non-covalent binding with G-C-rich duplex DNA in the presence of magnesium and zinc ions. Mithramycin also induces differentiation of leukemic cells accompanied by an early decrease in c-myc expression, and selectively inhibits collagen-1 gene expression in human fibroblasts.
0 India supplier list of "MITHRAMYCIN A"
- Product Name:MithramycinAfromStreptomycesplicatus
- Products Intro:Brand:sigma aldrich | Product Number:M6891 | Purity:≥90%(HPLC)
- Company Type: Trader
- Country/Region: INDIA
- Product Name:MithramycinA
- Products Intro:Brand:clearsynth | Product Number:CS-T-58858
- Company Type: Trader
- Country/Region: INDIA
- Product Name:MITHRAMYCIN A
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
$0.00/ 25KG
- Product Name:Mithramycin A
- Products Intro:Purity: 95%-99% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
$1.00/ 1kg
- Product Name:MITHRAMYCIN A
- Products Intro:Purity: 99%|Package: 1PCS;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1PCS
- Product Name:Mithramycin A
- Products Intro:Purity: >98% | CustNote: BOC Sciences also provides custom synthesis services for Mithramycin A.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Mithramycin A
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Mithramycin
- Products Intro:Purity: 99% | Package: 1kg; 25kg; or larger package as required
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Mithramycin
- Products Intro:Purity: 98% | Package: Package as requetsed
- Company Type: Trader
- Country/Region: CHINA
- Product Name:MITHRAMYCIN A
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g