Moxidectin manufacturers and suppliers in india

Moxidectin

Properties

Melting point:: 132 °C

Boiling point:: 790.0±70.0 °C(Predicted)

Density: 1.23±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: ≥128 mg/mL in EtOH; ≥129.4 mg/mL in DMSO; ≥3.27 mg/mL in H2O with gentle warming and ultrasonic

pka: 12.46±0.70(Predicted)

form: Solid

color: White to Almost white

Stability:: Light Sensitive

InChIKey: YZBLFMPOMVTDJY-LSGXYNIPSA-N

Safety Information

Symbol(GHS): GHS06,GHS09

Signal word: Danger

Hazard statements: H301-H400

Precautionary statements: P264-P270-P273-P301+P310-P391-P405

Hazard Codes: T,N

Risk Statements: 25-50

Safety Statements: 45-61-24/25

RIDADR: 2588

WGK Germany: 3

RTECS: PY5438800

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29322090

Use

Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. Moxidectin binds selectively to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.