Moxonidine
Moxonidine
- CAS:
- 75438-57-2
- MF:
- C9H12ClN5O
- MW:
- 241.68
Suppliers by country/region
Company Type
Properties
- Melting point:
- 217-219° (dec)
- Boiling point:
- 364.7±52.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
- pka
- 7.11±0.10(Predicted)
- form
- Solid
- color
- White to Almost white
- Water Solubility
- 800.3mg/L(temperature not stated)
- Merck
- 14,6293
- InChIKey
- WPNJAUFVNXKLIM-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS09,GHS06
- Signal word
- Danger
- Hazard statements
- H411-H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
- RIDADR
- UN 2811 6.1/PG III
- WGK Germany
- 3
- RTECS
- UV6260290
- HS Code
- 2933.99.5300
- HazardClass
- 6.1
- PackingGroup
- III
Use
Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata. Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure. It is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the 2-receptor. In contrast, clonidine binds to both receptors with equal affinity. It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure.
6 India supplier list of "Moxonidine"
- Product Name:4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy- 2-methyl-5-pyrimidinamine
- Products Intro:Purity: 98% | Package: 100 mg, 1 g, 100 g and 1 kg
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Moxonidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Moxonidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Moxonidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Moxonidine-d3
- Products Intro:Brand:synzeal | Product Number:499792123
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Moxonidine
- Products Intro:Brand:pharmaffiliates | Product Number:PA1356000
- Company Type: Trader
- Country/Region: Haryana,INDIA