Mycophenolic acid
Mycophenolic acid
- CAS:
- 24280-93-1
- MF:
- C17H20O6
- MW:
- 320.34
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Company Type
Properties
- Melting point:
- 141°C
- Boiling point:
- 419.24°C (rough estimate)
- Density
- 1.2300 (rough estimate)
- vapor pressure
- 0Pa at 22℃
- refractive index
- 1.5200 (estimate)
- Flash point:
- 2℃
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- methanol: 50 mg/mL, clear, colorless to faintly yellow
- form
- powder
- pka
- 4.5(at 25℃)
- color
- white to white with yellow cast
- Water Solubility
- 13mg/L(25 ºC)
- Merck
- 14,6327
- BRN
- 1295848
- BCS Class
- 2?
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
- LogP
- -1.83-2.28 at 25℃ and pH5-9
- Dissociation constant
- 4.58-8.05 at 22.5-25℃
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H302-H341-H360D-H372-H410
- Precautionary statements
- P201-P202-P260-P273-P301+P312-P308+P313
- Hazard Codes
- Xn,N,T,F
- Risk Statements
- 22-61-40-68-50/53-48/25-52/53-36-20/21/22-11
- Safety Statements
- 53-45-36/37-61-22-26-16
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- MP8050000
- F
- 10
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29419090
- Toxicity
- LD50 in mice (mg/kg): >1250 orally; 972.9±77 i.p. (Williams)
Use
Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumor, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.
4 India supplier list of "Mycophenolic acid "
- Product Name:Mycophenolic acid
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Mycophenolate Mofetil EP Impurity F Mycophenolic Acid
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Mycophenolic acid
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:MycophenolicAcid-CAS24280-93-1-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:475913 | Purity:Animmunosuppressiveagentthatinhibitsdenovopurinenucleotidesynthesisviainhibition
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Mycophenolic acid 95.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.076439
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:MycophenolateMofetilEPImpurityF
- Products Intro:Brand:synzeal | Product Number:182362544
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:MycophenolicAcid
- Products Intro:Brand:tcichemicals | Product Number:M2216
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Mycophenolicacid
- Products Intro:Brand:clearsynth | Product Number:CS-O-01857
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Mycophenolicacid
- Products Intro:Brand:chemsworth | Product Number:807371702
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:MycophenolicAcid
- Products Intro:Brand:pharmaffiliates | Product Number:PA1357060
- Company Type: Trader
- Country/Region: Haryana,INDIA