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Naphazoline hydrochloride

Naphazoline hydrochloride

CAS:
550-99-2
MF:
C14H14N2.ClH
MW:
246.74

Properties

Melting point:
254-260 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Freely soluble in water, soluble in ethanol (96 per cent).
form 
Crystalline Powder
pka
pKa (25°C) 10.35 ±0.02, (35°C) 10.13 ±0.02, (45°C) 9.92 ±0.03; pKa (25°C) 10.35 ±0.02, (35°C) 10.13 ±0.02, (45°C) 9.92 ±0.03
color 
White
PH
pH (50g/l, 25℃) : 4.0~6.0
Water Solubility 
170 g/L (20 ºC)
Sensitive 
Hygroscopic
Merck 
14,6368
BRN 
3716843
Stability:
Hygroscopic
InChIKey
DJDFFEBSKJCGHC-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS06
Signal word 
Danger
Hazard statements 
H300
Precautionary statements 
P264-P270-P301+P310+P330-P405-P501-P301+P310a-P321-P501a
Hazard Codes 
T,Xn
Risk Statements 
25-23/24/25-20/21/22
Safety Statements 
45-36/37/39-24/25
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
NJ4375000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339900
Toxicity
LD50 s.c. in rats: 385 mg/kg (Gylfe)

Use

Naphazoline hydrochloride, is commonly used as a vasoconstrictor in the hospital's otorhinolaryngology and ophthalmology ,it is a adrenomimetic drug ,it has a strong effect on contraction of blood vessels and blood pressure elevation,it has inhibition effect on the central nervous system,by contraction of local vascular, it can play an anti-inflammatory and analgesic role in the local inflammatory lesions , and can eliminate congestion due to fatigue or other reasons. Clinically it is used for the treatment of colds, acute and chronic rhinitis, allergic conjunctivitis, allergic and inflammatory nasal congestion embolism. Local long-term use can lead to blood flow reduction in medication area, which causes resistance decreasing , and results in superinfection. It can not be taken orally. Dropping excess liquid or high concentrations can cause poisoning. Care should be taken, especially in children. Infants, hypertension, hyperthyroidism patients should take with caution, atrophic rhinitis patients are banned. The interval time of dropping , is preferably not less than 4 to 6 hours. The above information is edited by the chemicalbook of Tian Ye.

33 India supplier list of "Naphazoline hydrochloride"

  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:NAPHAZOLINE NITRATE
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:Naphazoline Hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: INDIA
  • Product Name:Naphazoline hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: INDIA
  • Product Name:Naphazoline Hydrochloride
  • Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: INDIA

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