Nedaplatin
Nedaplatin
- CAS:
- 95734-82-0
- MF:
- C2H6N2O3Pt
- MW:
- 301.17
Suppliers by country/region
Company Type
Properties
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- H2O : 13.6 mg/mL (44.86 mM; Need ultrasonic and warming; DMSO can inactivate Nedaplatin's activity)DMF : < 1 mg/mL (insoluble; DMSO can inactivate Nedaplatin's activity)
- form
- Powder
- color
- Light yellow to yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
Use
Nedaplatin, a novel second generation platinum complex, was marketed in Japan for the treatment of a variety of cancers including: head and neck, small-cell and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder, and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more active than cisplatin against several solid tumors while sharing less nephro- and gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by nedaplatin allows its use in patients with deteriorated renal function.
1 India supplier list of "Nedaplatin"
- Product Name:Nedaplatin 98.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.085779
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Nedaplatin
- Products Intro:Brand:ajchemicals | Product Number:JDH-34860 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Nedaplatin
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Nedaplatin
- Products Intro:Purity: 98% | Package: 1KG;100USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$100.00/ 1KG
- Product Name:Nedaplatin
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:Nedaplatin
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Specialty chemical,UV Curing & Brightener,OLED Chemicals,CDMO SERVICES
- Product Name:Nedaplatin
- Products Intro:Package: 1KG;5KG;100KG;1000KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Nedaplatin
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Nedaplatin
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Nedaplatin
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes