Nifuratel manufacturers and suppliers in india

Nifuratel

Properties

Melting point:: 176-178°C

Boiling point:: 423.6±53.0 °C(Predicted)

Density: 1.57±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,Room Temperature

solubility: Acetone (Sparingly), DMSO (Slightly)

form: Solid

pka: -2.49±0.40(Predicted)

color: Yellow

Stability:: Hygroscopic

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Risk Statements: 68

Safety Statements: 36/37

HS Code: 29321900

Toxicity: LD50 oral in mouse: > 4500mg/kg

Use

Nifuratel is a derivative of nitrofuran , it is a broad spectrum antibiotic with broad-spectrum antimicrobial effect, Nystatin is a polyene antifungal,it has strong effects on trichomoniasis, bacteria, Candida albicans , it plays a strong killing role especially in common pathogens for gynecological infections such as gram-positive and gram-negative bacteria, trichomoniasis, mold, chlamydia and mycoplasma . After oral administration, it is absorbed by gastrointestinal ,most of it is excreted through the kidneys, it has higher concentrations in blood, urine, genital tissues ,so it can have a strong antibacterial effect in the urinary system, and its metabolites still have antibacterial activity, and it is excreted through the urine . Oral nifuratel can be rapidly absorbed, after oral administration of 200mg, the peak plasma concentration is 9.48μg/L in two hours . The animals acute toxicity test proves that in toxicity of the product is mild. Nifuratel indications include: 1, bacterial vaginosis, trichomonas vaginitis, vulvovaginal candidiasis, vaginal mixed infections. 2, urinary tract infections. 3, gastrointestinal amoebiasis and trichomoniasis Jia. The above information is edited by the chemicalbook of Tian Ye.