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Palmitoylethanolamide

PALMITOYLETHANOLAMIDE

CAS:
544-31-0
MF:
C18H37NO2
MW:
299.49

Properties

Melting point:
97-98℃
Boiling point:
461.5±28.0 °C(Predicted)
Density 
0.910±0.06 g/cm3(Predicted)
vapor pressure 
0.45Pa at 20℃
RTECS 
ML8950000
storage temp. 
-20°C
solubility 
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka
14.49±0.10(Predicted)
form 
White solid
color 
White
Water Solubility 
4.01mg/L at 20℃
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey
HXYVTAGFYLMHSO-UHFFFAOYSA-N
LogP
3.989 at 20℃

Safety Information

Symbol(GHS) 

GHS05,GHS09
Signal word 
Danger
Hazard statements 
H315-H318-H411
Precautionary statements 
P264-P273-P280-P302+P352-P305+P351+P338-P332+P313
WGK Germany 
2
TSCA 
Yes
HS Code 
2934.99.4400

Use

Palmitoylethanolamide (PEA) is an endogenous fatty acid mediator that is synthetized from membrane phospholipids by N-acyl phosphatidylethanolamine phospholipase D. Its biological actions are primarily mediated by PPAR-α (peroxisome proliferator-activated receptors α) and the orphan receptor GPR55. Palmitoylethanolamide exerts potent anti-inflammatory actions but its physiological role and promise as a therapeutic agent in chronic arterial inflammation, such as atherosclerosis remain unexplored. It was initially described as an agonist to the type 2 cannabinoid receptor (CB2), though it is now recognized that PEA does not bind to cannabinoid receptors. PEA is known to have anti-inflammatory, analgesic, and neuroprotective properties. PEA supplements have been used by people with chronic pain as well as those with neuropathic pain.

13 India supplier list of "PALMITOYLETHANOLAMIDE"

  • Product Name:Palmitoylethanolamide
  • Products Intro:Purity: 98% | Package: 25kg , Customized pack size availaible
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Palmidrol
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Palmitoylethanolamide
  • Products Intro:Purity: 98% | Package: 25kg, 100kg, 500kg
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Palmidrol
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Palmidrol
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Palmidrol
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Palmidrol
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Palmitoylethanolamide
  • Products Intro:Brand:sigma aldrich | Product Number:P0359
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Palmitoylethanolamide 98.00%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.091175
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Palmitoylethanolamide (PEA)
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA

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