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Phenobarbital
Phenobarbital
- CAS:
- 50-06-6
- MF:
- C12H12N2O3
- MW:
- 232.24
Properties
- Melting point:
- 174°C
- Boiling point:
- 374.4°C (rough estimate)
- Density
- 1.2243 (rough estimate)
- refractive index
- 1.6660 (estimate)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- Very slightly soluble in water, freely soluble in ethanol (96 per cent). It forms water-soluble compounds with alkali hydroxides, carbonates and ammonia.
- pka
- 7.3, 11.8(at 25℃)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- <0.01 g/100 mL at 14 ºC
- Merck
- 13,7319
- BCS Class
- 1
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS08,GHS06
- Signal word
- Danger
- Hazard statements
- H317-H351-H301+H311+H331
- Precautionary statements
- P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501
- Hazard Codes
- T,F
- Risk Statements
- 61-25-40-43-39/23/24/25-23/24/25-11
- Safety Statements
- 53-36/37-45-16
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- CQ6825000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933530000
- Toxicity
- LD50 orally in rats: 162 ±14 mg/kg (Goldenthal)
Use
Phenobarbital, also known as Rumina and Canaa, is white andglossy crystalline powder. This product has sedative, hypnotic and anticonvulsant effects, and can resist epilepsy. It is effective for large epileptic seizures, localized seizures and status epilepticus. It also enhances the role of antipyretic analgesics, and can induce liver microsomal glucuronosyltransferase activity, promote bilirubin and glucuronic acid binding, reduce plasma bilirubin concentration, and treat neonatal cerebral nucleus jaundice.
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