Phenoxybenzamine hydrochloride manufacturers and suppliers in india

Phenoxybenzamine hydrochloride

Properties

Melting point:: 137.5°C

storage temp.: 15-25°C

solubility: soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).

form: powder

pka: pKa 4.4 (Uncertain)

color: white

Water Solubility: <0.01 g/100 mL at 18.5 ºC

Merck: 14,7256

Stability:: Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Warning

Hazard statements: H302-H351

Precautionary statements: P201-P301+P312+P330-P308+P313

Hazard Codes: Xn

Risk Statements: 22-40

Safety Statements: 22-36/37/39-45

WGK Germany: 3

RTECS: DP3750000

HS Code: 2922299000

Use

Phenoxybenzamine (5.0 to 60.0 mg/day) is used in order to control episodes of hypertension and sweating, it has a relatively slow onset and prolonged effect when compared to alternative α-blockers. If tachycardia is excessive, it may also be necessary to use a betablocker concomitantly. In addition, phenoxybenzamine has been tested for its efficacy in micturition disorders resulting from neurogenic bladder, functional outlet obstruction, and partial prostatic obstruction.