PIK-294
PIK-294
- CAS:
- 900185-02-6
- MF:
- C28H23N7O2
- MW:
- 489.53
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 790.4±70.0 °C(Predicted)
- Density
- 1.43
- storage temp.
- -20°C
- solubility
- ≥24.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- form
- powder
- pka
- 8.95±0.10(Predicted)
- color
- white to beige
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P310+P330
- RIDADR
- UN 2811 6.1 / PGIII
Use
PIK-294 shows distinct patterns of isoform selectivity to inhibit different subsets of class I PI3K isoforms (p110β, p110δ, and p110γ) and exhibits low sensitivity to p110α with IC50 of 10 μM). The m-phenol moiety of PIK-294 is able to penetrate the deep-affinity pocket of the ATP binding site, and thus increases in vitro inhibitory activity.
1 India supplier list of "PIK-294"
- Product Name:PIK-294
- Products Intro:Brand:sigma aldrich | Product Number:SML1381 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:PIK-294 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089136
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PIK-294
- Products Intro:Brand:clearsynth | Product Number:CS-T-39964
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:PIK-294
- Products Intro:Purity: 0.99 | Package: 5MG;10MG;50MG;100MG,1G,5G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:2-((4-amino-3-(3-hydroxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)methyl)-5-methyl-3-(2-methylphenyl)-4(3h)-quinazolinone
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:PIK-294；PIK294;PIK 294
- Products Intro:Purity: 99.00% | Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:PIK-294
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AR-12 OSU-03012
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:PIK-294
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
- Product Name:PIK-294
- Products Intro:Purity: >=98% | Package: $36.9/1mg;$78.9/5mg;$137.9/10mg;$310.9/25mg;$345.9/50mg;$543.9/100mg;Bulk packag | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies