Pimozide
PIMOZIDE
- CAS:
- 2062-78-4
- MF:
- C28H29F2N3O
- MW:
- 461.55
Suppliers by country/region
Company Type
Properties
- Melting point:
- 214-218°
- Density
- 1.1763 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: 18 mg/mL
- pka
- 7.32(at 25℃)
- form
- White solid
- color
- Off-White to Light Orange
- Water Solubility
- 2.9mg/L(30 ºC)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 36
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- DE1750000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933399090
Use
Pimozide, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone (Orap), isa white to creamy white solid (pKa＝9.42). Pimozide is 50%absorbed after oral administration. It is metabolized byCYP450 enzymes, in particular the CYP3A4 and CYP1A2isozymes, to inactive metabolites. Pimozide is excreted in theurine and to a lesser extent in the feces. Toxic effects may beproduced with pimozide in the presence of inducers or inhibitorsof CYP3A4 and CYP1A2. Pimozide is also a stronginhibitor of CYP2D6 without appearing to be an importantsubstrate of this isoform.99 The use of pimozide in the UnitedStates is small, but it is a critical drug for many patients withGilles de la Tourette disorder who cannot tolerate haloperidol.
12 India supplier list of "PIMOZIDE"
- Product Name:Pimozide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Pimozide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Pimozide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Pimozide
- Products Intro:Brand:sigma aldrich | Product Number:P1793
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Pimozide >98% (HPLC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.071340
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PIMOZIDE
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PIMOZIDE
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PIMOZIDE
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Pimozide
- Products Intro:Brand:clearsynth | Product Number:CS-O-11715
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:PIMOZIDE
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA