Probenecid manufacturers and suppliers in india

Probenecid

Properties

Melting point:: 194-196°C

Boiling point:: 438.0±47.0 °C(Predicted)

Density: 1.2483 (rough estimate)

refractive index: 1.6800 (estimate)

storage temp.: Store at RT

solubility: DMSO (Slightly), Methanol (Slightly)

pka: 5.8(at 25℃)

form: Solid

color: White to Off-White

Water Solubility: <0.1 g/100 mL at 20 ºC

Merck: 14,7754

Stability:: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 22-40

Safety Statements: 36/37-24/25

RIDADR: 3249

WGK Germany: 3

RTECS: DG9400000

TSCA: Yes

HS Code: 29350090

Use

Probenecid is a kind of anti-gout drug. The product is organic acid, strongly fat-soluble, self-discharge from tubular secretion, very easily to be absorbed back. Therefore, in the presence of probenecid, the transfer of some organic acids in the tubular body will be inhibited, reducing the excretion of other organic acids. Thereby, it is used to treat chronic gout with being safe and effective. It has no effects on acute gout pain and inflammation and can’t be applied to acute gout. It is used for the treatment of gout, rheumatoid arthritis and other chronic diseases.