Probucol
Probucol
- CAS:
- 23288-49-5
- MF:
- C31H48O2S2
- MW:
- 516.84
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Company Type
Properties
- Melting point:
- 126-128°C
- Boiling point:
- 571.58°C (rough estimate)
- Density
- 1.0008 (rough estimate)
- refractive index
- 1.5341 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 10.27±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
- Merck
- 14,7755
- InChIKey
- FYPMFJGVHOHGLL-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
- WGK Germany
- 2
- RTECS
- AL3705000
- HS Code
- 2930902000
Use
Probucol, 4,4' -[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol], DH-581(Lorelco), is a chemical agent that was developed for the plasticsand rubber industry in the 1960s. The probucol moleculehas two tertiary butylphenol groups linked by a dithiopropylidenebridge, giving it a high lipophilic character with strongantioxidant properties. In humans, it causes reduction of bothliver and serum cholesterol levels, but it does not alter plasmatriglycerides. It reduces LDL and (to a lesser extent) HDLlevels by a unique mechanism that is still not clearly delineated.The reduction of HDL may be caused by the ability ofprobucol to inhibit the synthesis of apoprotein A-1, a majorprotein component of HDL. It is effective at reducing levelsof LDL and is used in hyperlipoproteinemias characterized byelevated LDL levels.
1 India supplier list of "Probucol"
- Product Name:Probucol
- Products Intro:Brand:sigma aldrich | Product Number:P9672 | Purity:analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Probucol
- Products Intro:Brand:pharmaffiliates | Product Number:PA6935000
- Company Type: Trader
- Country/Region: INDIA