SGI-1027
SGI-1027
- CAS:
- 1020149-73-8
- MF:
- C27H23N7O
- MW:
- 461.52
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Properties
- Melting point:
- >280℃
- Density
- 1.387±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO (up to 35 mg/ml)
- pka
- 13.31±0.70(Predicted)
- form
- powder
- color
- white to light brown
- Stability:
- Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
Use
SGI-1027 inhibits DNA methylation by directly inhibiting DNMTs, and results in selective degradation of DNMT1 in a wide variety of human cancer cell lines. SGI-1027 exhibits minimal or no cytotoxic effect in rat hepatoma H4IIE cells. SGI-1027 (0-100 M) exhibits a moderate pro-apoptotic effect on U937 human leukemia cell line with no relevant changes on the cell cycle.
0 India supplier list of "SGI-1027"
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- Product Name:SGI-1027
- Products Intro:Brand:sigma aldrich | Product Number:SML1358 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:SGI 1027
- Products Intro:Purity: >=98% (HPLC) | Package: $83.9/5mg;$133.9/10mg;$301.9/25mg;$402.9/50mg;$725.9/100mg;Bulk package | CustNote: 98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies