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Sildenafil
Sildenafil
- CAS:
- 139755-83-2
- MF:
- C22H30N6O4S
- MW:
- 474.58
Properties
- Melting point:
- 187-189°C
- Density
- 1.39±0.1 g/cm3(Predicted)
- Flash point:
- 9℃
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- pKa 8.7 (Uncertain)
- color
- White to Off-White
- InChIKey
- BNRNXUUZRGQAQC-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H301+H311+H331-H370
- Precautionary statements
- P210-P260-P280-P301+P310-P311
- Hazard Codes
- Xi,T,F
- Risk Statements
- 36/37/38-39/23/24/25-23/24/25-11
- Safety Statements
- 22-24/25-36-26-45-36/37-16-7
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 1
- HS Code
- 38220090
Use
Sildenafil, the first US FDA-approved, oral phosphodiesterase type-5 inhibitor, has revolutionized the treatment of erectile dysfunction sine its approval in 1998. Since sildenafil is a potent inhibitor of cyclic guanosine monophosphate in the corpus cavernosum and therefore increases the penile response to sexual stimulation.
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