Sulfanilamide
Sulfanilamide
- CAS:
- 63-74-1
- MF:
- C6H8N2O2S
- MW:
- 172.2
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Company Type
Properties
- Melting point:
- 164-166 °C(lit.)
- Boiling point:
- 400.5±47.0 °C(Predicted)
- Density
- 1.08
- vapor pressure
- 0.00001 hPa (70 °C)
- refractive index
- 1.6490 (estimate)
- storage temp.
- 2-8°C
- solubility
- 5.37g/l
- pka
- pKa 10.65(H2O t = 25.0±0.5 I = 0.2) (Uncertain)
- form
- powder
- color
- white to faintly beige
- PH
- 5.8-6.1 (5g/l, H2O, 20℃)
- Odor
- Odorless
- PH Range
- 5.8 - 6.1 (0.5% aq.sol.)
- Water Solubility
- 7.5 g/L at 25 ºC
- λmax
- 257nm(H2O)(lit.)
- Merck
- 14,8925
- BRN
- 511852
- InChIKey
- FDDDEECHVMSUSB-UHFFFAOYSA-N
- LogP
- -0.620
Safety Information
- Symbol(GHS)
GHS07,GHS05
- Signal word
- Warning
- Hazard statements
- H303-H315-H314-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P260h-P301+P330+P331-P303+P361+P353
- Hazard Codes
- Xn
- Risk Statements
- 40
- Safety Statements
- 24/25-36-22
- WGK Germany
- 3
- RTECS
- WO8400000
- F
- 10
- TSCA
- Yes
- HazardClass
- 8
- HS Code
- 29350090
- Toxicity
- LD50 orally in mice: 3.8 g/kg (Marshall)
Use
Sulfanilamide is a sulfonamide antibiotic. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.Formulations containing sulfanilamide have been used to treat T. vaginalis infections. It is bacteriostatic against Streptococci in vitro at a concentration of 20 g/ml and inhibits the growth of 106 clinically isolated strains of Gonococcus.Sulfanilamide reduces the concentration of Streptococcus in rabbit plasma ex vivo following four doses of 20 ml of a 2% sulfanilamide solution. Mode of Action: A competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
29 India supplier list of "Sulfanilamide"
- Product Name:Sulfanilamide, 98%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Sulfanilamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA