Sulfathiazole manufacturers and suppliers in india

Sulfathiazole

Properties

Melting point:: 200-202 °C (lit.)

Boiling point:: 479.5±47.0 °C(Predicted)

Density: 1.4629 (rough estimate)

refractive index: 1.6560 (estimate)

storage temp.: 2-8°C

solubility: 0.5g/l

pka: 7.2(at 25℃)

form: Solid

color: White

Water Solubility: Insoluble (<0.1 g/100 mL at 21 ºC)

Merck: 14,8943

BRN: 226178

Stability:: Stable. Incompatible with strong oxidizing agents.

InChIKey: JNMRHUJNCSQMMB-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335-H412

Precautionary statements: P261-P264-P271-P273-P302+P352-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36

RIDADR: 3249

WGK Germany: 2

RTECS: WP2360000

TSCA: Yes

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29350090

Use

2-Sulfanilamidothiazole. A short-acting compound (half-life c. 4 h) with relatively high activity. Protein binding is c. 75%. Its use has declined because of a high incidence of side effects. It is one of the constituents of triple sulfonamide mixtures, of which local preparations are still available. Two compounds, phthalylsulfathiazole (sulfathalidine) and succinylsulfathiazole (sulfasuxidine) owe their activity to the slow liberation of sulfathiazole in the bowel. They are poorly soluble and very little is absorbed after oral administration. They were formerly used in the treatment of intestinal infections and in bowel preparation before surgery. They are available in multi-ingredient preparations in some countries.